cPanel and Plesk both are different control panels with a different user interface. cPanel control panel is supported on Linux based hosting plans and servers only, whereas, Plesk is supported on Linux as well as Windows based hosting plans and servers. Both these control panels are licensed applications, however, the licensing fee of the control panel may vary according to the control panel you choose.
cPanel control panel is available for unlimited domains only, whereas, Plesk offers options when it comes to the number of domains you can host and hence you have options while choosing Plesk control panel. As for now, cPanel control panel is considered to be the best control panel for Linux based hosting plans and servers, whereas, Plesk is generally preferred for Windows based hosting plans and servers.
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